Conjugation of Aztreonam, a Synthetic Monocyclic β-Lactam Antibiotic, to a Siderophore Mimetic Significantly Expands Activity Against Gram-Negative Bacteria
Author:
Affiliation:
1. Department of Chemistry and Biochemistry, University of Notre Dame, Notre Dame, Indiana 46556, United States
Funder
University of Notre Dame
National Institute of Allergy and Infectious Diseases
Publisher
American Chemical Society (ACS)
Subject
Infectious Diseases
Link
https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.1c00458
Reference39 articles.
1. O’Neill, J Tackling Drug-Resistant Infections Globally: Final Report and Recommendations; Review on Antimicrobial Resistance: London, 2016; pp 1–84. https://www.chathamhouse.org/sites/default/files/publications/research/2019-10-11-AMR-Full-Paper.pdf (accessed 2021-10-01).
2. A facile synthesis of substituted N-hydroxy-2-azetidinones. A biogenetic type .beta.-lactam synthesis
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