Synthesis and <i>In Vitro</i> Biological Evaluation of Quinolinyl Pyrimidines Targeting Type II NADH-Dehydrogenase (NDH-2)-Reference-Cited by-同舟云学术

Synthesis and In Vitro Biological Evaluation of Quinolinyl Pyrimidines Targeting Type II NADH-Dehydrogenase (NDH-2)

Published:2022-02-21 Issue:3 Volume:8 Page:482-498
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Lu Lu¹,Åkerbladh Linda²,Ahmad Shabbir¹,Konda Vivek²,Cao Sha³,Vocat Anthony⁴,Maes Louis⁵,Cole Stewart T.⁴,Hughes Diarmaid³,Larhed Mats⁶^ORCID,Brandt Peter²,Karlén Anders²,Mowbray Sherry L.¹⁷^ORCID

Affiliation:

1. Department of Cell and Molecular Biology, BMC, Uppsala University, Box 596, SE-751 24 Uppsala, Sweden

2. Department of Medicinal Chemistry, Organic Pharmaceutical Chemistry, BMC, Uppsala University, Box 574, SE-751 23 Uppsala, Sweden

3. Department of Medical Biochemistry and Microbiology, BMC, Uppsala University, Box 582, SE-751 23 Uppsala, Sweden

4. École Polytechnique Fédérale de Lausanne, EPFL SV/GHI/UPCOL, Global Health Institute, Station no. 19, CH-1015 Lausanne, Switzerland

5. Laboratory of Microbiology, Parasitology and Hygiene (LMPH), University of Antwerp, Universiteitsplein 1, B-2610 Antwerp, Belgium

6. Department of Medicinal Chemistry, Science for Life Laboratory, BMC, Uppsala University, Box 574, SE-751 23 Uppsala, Sweden

7. Department of Cell and Molecular Biology, Science for Life Laboratory, BMC, Uppsala University, Box 596, SE-751 24 Uppsala, Sweden

Funder

Svenska Forskningsr?det Formas

Science for Life Laboratory

Vetenskapsr?det

Uppsala Universitet

Sixth Framework Programme

Seventh Framework Programme

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Link

https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.1c00413

Reference26 articles.

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3. WHO. Global Tuberculosis Report 2020. https://apps.who.int/iris/bitstream/handle/10665/336069/9789240013131-eng.pdf (accessed Feb 4, 2021).

4. Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America

5. ECDC/EMEA Joint Technical Report: The Bacterial Challenge: Time to React; European Centre for Disease Prevention and Control, 2009.

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