Targeting the Bacterial Epitranscriptome for Antibiotic Development: Discovery of Novel tRNA-(N1G37) Methyltransferase (TrmD) Inhibitors-Reference-Cited by-同舟云学术

Targeting the Bacterial Epitranscriptome for Antibiotic Development: Discovery of Novel tRNA-(N1G37) Methyltransferase (TrmD) Inhibitors

Published:2019-01-25 Issue:3 Volume:5 Page:326-335
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Zhong Wenhe¹²^ORCID,Koay Ann³,Ngo Anna³,Li Yan³,Nah Qianhui¹,Wong Yee Hwa²⁴,Chionh Yok Hian¹,Ng Hui Qi³,Koh-Stenta Xiaoying³,Poulsen Anders³^ORCID,Foo Klement³,McBee Megan¹,Choong Meng Ling³,El Sahili Abbas²⁴,Kang Congbao³^ORCID,Matter Alex³,Lescar Julien¹²⁴,Hill Jeffrey³,Dedon Peter¹⁵

Affiliation:

1. Antimicrobial Resistance Interdisciplinary Research Group, Singapore-MIT Alliance for Research and Technology, 1 CREATE Way, 138602 Singapore

2. NTU Institute of Structural Biology, Nanyang Technological University, 636921 Singapore

3. Experimental Therapeutics Centre, 31 Biopolis Way, #03-01 Nanos, 138669 Singapore

4. School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, 637551 Singapore

5. Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, United States

Funder

Agency for Science, Technology and Research

Ministry of Education - Singapore

National Research Foundation Singapore

Singapore-MIT Alliance for Research and Technology Centre

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Link

http://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.8b00275

Reference34 articles.

1. Tackling antibiotic resistance

2. O’Neill, J. Antimicrobial Resistance: Tackling a crisis for the health and wealth of nations. 2014.

3. Meet WHO's dirty dozen: The 12 bacteria for which new drugs are most urgently needed

4. Centers for Disease Control and Prevention. Antibiotic Resistance Threats in the United States, 2013. 2013.

5. Understanding RNA modifications: the promises and technological bottlenecks of the ‘epitranscriptome’

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