Discovery and Characterization of 2-Nitro-5-(4-(phenylsulfonyl)piperazin-1-yl)-N-(pyridin-4-ylmethyl)anilines as Novel Inhibitors of the Aedes aegypti Kir1 (AeKir1) Channel
Author:
Affiliation:
1. Department of Anesthesiology, Vanderbilt University Medical Center, Nashville, Tennessee 37232, United States
2. Department of Entomology, Ohio State University, Wooster, Ohio 44691, United States
Funder
National Institute of Allergy and Infectious Diseases
Publisher
American Chemical Society (ACS)
Subject
Infectious Diseases
Link
https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.8b00368
Reference26 articles.
1. WHO (2014) A global brief on vector-borne diseases, p 54, http://www.who.int/iris/handle/10665/111008.
2. Economic Impact of Dengue Illness in the Americas
3. Economic and Disease Burden of Dengue in Southeast Asia
4. Reemergence of Chikungunya Virus
5. Chikungunya Virus and the Global Spread of a Mosquito-Borne Disease
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2. The Molecular Physiology and Toxicology of Inward Rectifier Potassium Channels in Insects;Annual Review of Entomology;2022-01-07
3. Novel inhibitors of the renal inward rectifier potassium channel of the mosquito vector Aedes aegypti;Future Medicinal Chemistry;2021-11
4. Further SAR on the (Phenylsulfonyl)piperazine Scaffold as Inhibitors of the Aedes aegypti Kir1 ( Ae Kir) Channel and Larvicides;ChemMedChem;2020-10-28
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