In Vitro and In Vivo Characterization of the Anti-Zika Virus Activity of ProTides of 2′-C-β-Methylguanosine-Reference-Cited by-同舟云学术

In Vitro and In Vivo Characterization of the Anti-Zika Virus Activity of ProTides of 2′-C-β-Methylguanosine

Published:2020-06-11 Issue:7 Volume:6 Page:1650-1658
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Matos de Souza Marcos Romário^ORCID,Cunha Marcela Sabino,Okon Aniekan¹,Monteiro Fábio Luís Lima,Campanati Loraine,Wagner Carston R.¹^ORCID,da Costa Luciana Jesus^ORCID

Affiliation:

1. Department of Medicinal Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States

Funder

Conselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico

University of Minnesota

Funda??o Carlos Chagas Filho de Amparo ? Pesquisa do Estado do Rio de Janeiro

Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Link

https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.0c00091

Reference39 articles.

1. Milestones in the discovery of antiviral agents: nucleosides and nucleotides

2. Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases

3. Medicinal Chemistry of Nucleoside Phosphonate Prodrugs for Antiviral Therapy

4. Engineering Kinases to Phosphorylate Nucleoside Analogs for Antiviral and Cancer Therapy

5. INX-08189, a Phosphoramidate Prodrug of 6-O-Methyl-2′-C-Methyl Guanosine, Is a Potent Inhibitor of Hepatitis C Virus Replication with Excellent Pharmacokinetic and Pharmacodynamic Properties

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