Target-Based Design of Promysalin Analogues Identifies a New Putative Binding Cleft in Succinate Dehydrogenase-Reference-Cited by-同舟云学术

Target-Based Design of Promysalin Analogues Identifies a New Putative Binding Cleft in Succinate Dehydrogenase

Published:2020-04-14 Issue:6 Volume:6 Page:1372-1377
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

Post Savannah J.¹,Keohane Colleen E.¹,Rossiter Lauren M.²,Kaplan Anna R.¹,Khowsathit Jittasak³,Matuska Katie¹,Karanicolas John³^ORCID,Wuest William M.¹⁴^ORCID

Affiliation:

1. Department of Chemistry, Emory University, Atlanta, Georgia 30322, United States

2. Department of Chemistry, Temple University, Philadelphia, Pennsylvania 19122, United States

3. Molecular Therapeutics Program, Fox Chase Cancer Center, Philadelphia, Pennsylvania 19111, United States

4. Emory Antibiotic Resistance Center, Emory School of Medicine, Emory University, Atlanta, Georgia 30322, United States

Funder

Division of Chemistry

National Cancer Institute

Division of Graduate Education

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Link

https://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.0c00024

Reference31 articles.

1. Biggest Threats and Data. CDC’s Antibiotic Resistance Threats Report, 2019.

2. Platforms for antibiotic discovery

3. Chemical Strategies To Target Bacterial Virulence

4. Emergence and spread of antibiotic resistance following exposure to antibiotics

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