Structure–Activity Relationships of Pyrazolo[1,5-a]pyrimidin-7(4H)-ones as Antitubercular Agents

Author:

Oh Sangmi1ORCID,Libardo M. Daben J.1,Azeeza Shaik1,Pauly Gary T.2,Roma Jose Santinni O.1,Sajid Andaleeb1,Tateishi Yoshitaka1,Duncombe Caroline1,Goodwin Michael1,Ioerger Thomas R.3,Wyatt Paul G.4ORCID,Ray Peter C.4,Gray David W.4,Boshoff Helena I. M.1ORCID,Barry Clifton E.15ORCID

Affiliation:

1. Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States

2. Chemical Biology Laboratory, National Cancer Institute, Frederick, Maryland 21702, United States

3. Department of Computer Science and Engineering, Texas A&M University, College Station, Texas 77843, United States

4. Drug Discovery Unit, Division of Biological Chemistry and Drug Discovery, School of Life Sciences, University of Dundee, Dundee DD1 5EH, United Kingdom

5. Institute for Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town 7935, South Africa

Funder

National Institute of Allergy and Infectious Diseases

Foundation for the National Institutes of Health

Bill and Melinda Gates Foundation

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

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