Pharmacokinetic/Pharmacodynamic Determination and Preclinical Pharmacokinetics of the β-Lactamase Inhibitor ETX1317 and Its Orally Available Prodrug ETX0282-Reference-Cited by-同舟云学术

Pharmacokinetic/Pharmacodynamic Determination and Preclinical Pharmacokinetics of the β-Lactamase Inhibitor ETX1317 and Its Orally Available Prodrug ETX0282

Published:2020-05-07 Issue:6 Volume:6 Page:1378-1388
ISSN:2373-8227
Container-title:ACS Infectious Diseases
language:en
Short-container-title:ACS Infect. Dis.

Author:

O’Donnell John¹^ORCID,Tanudra Angela¹,Chen April¹,Hines Daniel¹,Tommasi Ruben¹^ORCID,Mueller John¹^ORCID

Affiliation:

1. Entasis Therapeutics 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States

Funder

Bundesministerium f?r Bildung und Forschung

Office of Public Health Preparedness and Response

Wellcome Trust

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

Link

http://pubs.acs.org/doi/pdf/10.1021/acsinfecdis.0c00019

Reference49 articles.

1. Resistance in Gram-Negative Bacteria: Enterobacteriaceae

2. Antibiotic resistance in Enterobacteriaceae: mechanisms and clinical implications

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5. Fluoroquinolone resistance: mechanisms, impact on bacteria, and role in evolutionary success

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