Effective Strategy Targeting Polymyxin-Resistant Gram-Negative Pathogens: Polymyxin B in Combination with the Selective Serotonin Reuptake Inhibitor Sertraline

Author:

Hussein Maytham1ORCID,Schneider-Futschik Elena K.1ORCID,Paulin Olivia K. A.1,Allobawi Rafah1,Crawford Simon2,Zhou Qi Tony3ORCID,Hanif Adil1,Baker Mark4,Zhu Yan5,Li Jian5ORCID,Velkov Tony1ORCID

Affiliation:

1. Department of Pharmacology & Therapeutics, School of Biomedical Sciences, Faculty of Medicine, Dentistry and Health Sciences, The University of Melbourne, Parkville, Victoria 3010, Australia

2. The Monash Ramaciotti Centre for Cryo-Electron Microscopy, Monash University, Clayton, Victoria 3800, Australia

3. Department of Industrial and Physical Pharmacy, College of Pharmacy, Purdue University, West Lafayette, Indiana 47907-2091, United States

4. Discipline of Biological Sciences, Priority Research Centre in Reproductive Biology, Faculty of Science and IT, University of Newcastle, University Drive, Callaghan, New South Wales 2308, Australia

5. Monash Biomedicine Discovery Institute, Department of Microbiology, Monash University, Clayton, Victoria 3800, Australia

Funder

U.S. Department of Health and Human Services

Department of Health, Australian Government

Publisher

American Chemical Society (ACS)

Subject

Infectious Diseases

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