Combined Effect of Platination and Intercalation upon DNA Binding of Novel Cytotoxic Pt−Bis(naphthalimide) Complexes-Reference-Cited by-同舟云学术

Combined Effect of Platination and Intercalation upon DNA Binding of Novel Cytotoxic Pt−Bis(naphthalimide) Complexes

Published:1999-12-01 Issue:26 Volume:42 Page:5482-5486
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Pérez José M.¹,López-Solera Isabel¹,Montero Eva I.¹,Braña Miguel F.¹,Alonso Carlos¹,Robinson Simon P.¹,Navarro-Ranninger Carmen¹

Affiliation:

1. Departamento de Química Inorgánica, Universidad Autónoma de Madrid, 28049 Madrid, Spain, Universidad San Pablo CEU, Madrid, Spain, Centro de Biología Molecular “Severo Ochoa”, CSIC-Universidad Autónoma de Madrid, 28049 Madrid, Spain, and BASF Bioresearch Corporation, Worcester, Massachusetts 01605

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm991099r

Reference29 articles.

1. Improved understanding in platinium antitumour chemistry

2. Modulation of platinum antitumor drug binding to DNA by linked and free intercalators

3. Preparation, characterization, and anticancer activity of a series of cis-PtCl2 complexes linked to anthraquinone intercalators

4. DNA-directed alkylating agents. 3. Structure-activity relationships for acridine-linked aniline mustards: consequences of varying the length of the linker chain

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