Prodrugs of Anthracyclines for Use in Antibody-Directed Enzyme Prodrug Therapy-Reference-Cited by-同舟云学术

Prodrugs of Anthracyclines for Use in Antibody-Directed Enzyme Prodrug Therapy

Published:1998-08-21 Issue:19 Volume:41 Page:3572-3581
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Florent Jean-Claude¹,Dong Xia¹,Gaudel Gilbert¹,Mitaku Sofia¹,Monneret Claude¹,Gesson Jean-Pierre¹,Jacquesy Jean-Claude¹,Mondon Martine¹,Renoux Brigitte¹,Andrianomenjanahary Solo¹,Michel Sylvie¹,Koch Michel¹,Tillequin François¹,Gerken Manfred¹,Czech Joerg¹,Straub Rainer¹,Bosslet Klaus¹

Affiliation:

1. UMR 176 CNRS/Institut Curie, Section Recherche, 26 rue d'Ulm, F-75248 Paris Cedex 05, France, Laboratoire de Chimie XII, Université de Poitiers, 26 rue du Dr. Pineau, 86022 Poitiers Cedex, France, Laboratoire de Pharmacognosie, 4 avenue de l'Observatoire, F-75005 Paris, France, and Hoechst Marion Roussel, P.O. Box 1140, D-35001 Marburg, Germany

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm970589l

Reference40 articles.

1. Antibody directed enzymes revive anti-cancer prodrugs concept

2. A cytotoxic agent can be generated selectively at cancer sites

3. Anti-tumor effects of antibody-alkaline phosphatase conjugates in combination with etoposide phosphate.

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