Structure-Guided Design and Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease. Structure–Activity Relationships and Biochemical, X-ray Crystallographic, Cell-Based, and In Vivo Studies-Reference-Cited by-同舟云学术

Structure-Guided Design and Optimization of Dipeptidyl Inhibitors of Norovirus 3CL Protease. Structure–Activity Relationships and Biochemical, X-ray Crystallographic, Cell-Based, and In Vivo Studies

Published:2015-03-19 Issue:7 Volume:58 Page:3144-3155
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Galasiti Kankanamalage Anushka C.¹,Kim Yunjeong²,Weerawarna Pathum M.¹,Uy Roxanne Adeline Z.¹,Damalanka Vishnu C.¹,Mandadapu Sivakoteswara Rao¹,Alliston Kevin R.¹,Mehzabeen Nurjahan³,Battaile Kevin P.⁴,Lovell Scott³,Chang Kyeong-Ok²,Groutas William C.¹

Affiliation:

1. Department of Chemistry, Wichita State University, 1845 North Fairmount Avenue, Wichita, Kansas 67260, United States

2. Department of Diagnostic Medicine & Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, Kansas 66506, United States

3. Protein Structure Laboratory,The University of Kansas, Lawrence, Kansas 66047, United States

4. IMCA-CAT, Hauptman-Woodward Medical Research Institute, APS Argonne National Laboratory, Argonne, Illinois 60439, United States

Funder

National Institute of Allergy and Infectious Diseases

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm5019934

Reference55 articles.

1. Progress towards the prevention and treatment of norovirus infections

2. Norovirus in healthcare settings

3. Norovirus Gastroenteritis in Immunocompromised Patients

4. Gastroenteritis in US Marines during Operation Iraqi Freedom

5. Efficacy of Commonly Used Disinfectants for Inactivation of Human Noroviruses and Their Surrogates

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