Rational Design of Partial Agonists for the Muscarinic M1 Acetylcholine Receptor

Author:

Chen Xinyu12,Klöckner Jessika1,Holze Janine3,Zimmermann Cornelia3,Seemann Wiebke K.4,Schrage Ramona3,Bock Andreas5,Mohr Klaus3,Tränkle Christian3,Holzgrabe Ulrike1,Decker Michael12

Affiliation:

1. Institute of Pharmacy and Food Chemistry, University of Würzburg, Am Hubland, 97074 Würzburg, Germany

2. Institute of Pharmacy, University of Regensburg, Universitätsstrasse 31, 93053 Regensburg, Germany

3. Pharmacology and Toxicology Section, Institute of Pharmacy, University of Bonn, Gerhard-Domagk-Strasse 3, 53121 Bonn, Germany

4. Department of Pharmacology, University of Cologne, Gleueler Strasse 24, 50931 Cologne, Germany

5. Institute of Pharmacology and Toxicology, University of Würzburg, Versbacher Strasse 9, 97078 Würzburg, Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

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