1. School of Biomedical and Health Sciences, Pharmaceutical Science Division, King’s College London, Franklin Wilkins Building, Stamford Street, London SE1 9NH, United Kingdom, School of Biosciences, University of Cardiff, Main Building, Park Place, Cardiff CF10 3TL, United Kingdom, and Department of Biomolecular Medicine, Division of Surgery, Oncology, Reproductive Biology, and Anaesthetics, Faculty of Medicine, Imperial College London, Sir Alexander Fleming Building, London SW7 2AZ, United Kingdom