1. Center for Research at Bio/nano Interface, Department of Chemistry and Department of Physiology and Functional Genomics, Shands Cancer Center, UF Genetics Institute and McKnight Brain Institute, University of Florida, Gainesville, Florida 32611-7200, and Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, 101, Sec 2, Kuang Fu Road, Hsinchu, Taiwan, ROC 30013