Structure–Activity Relationships of Cyanoquinolines with Corrector–Potentiator Activity in ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator Protein-Reference-Cited by-同舟云学术

Structure–Activity Relationships of Cyanoquinolines with Corrector–Potentiator Activity in ΔF508 Cystic Fibrosis Transmembrane Conductance Regulator Protein

Published:2012-01-23 Issue:3 Volume:55 Page:1242-1251
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Knapp John M.¹,Wood Alex B.¹,Phuan Puay-Wah²,Lodewyk Michael W.¹,Tantillo Dean J.¹,Verkman A. S.²,Kurth Mark J.¹

Affiliation:

1. Department of Chemistry, University of California, Davis, California 95616, United States

2. Departments of Medicine and Physiology, University of California, San Francisco, California 94143-0521, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm201372q

Reference46 articles.

1. Altered chloride ion channel kinetics associated with the ΔF508 cystic fibrosis mutation

2. An Animal Model for Cystic Fibrosis Made by Gene Targeting

3. Cystic fibrosis: a disease of vulnerability to airway surface dehydration

4. Peripheral Protein Quality Control Removes Unfolded CFTR from the Plasma Membrane

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