Discovery of Potent and Selective Adamantane-Based Small-Molecule P2X7 Receptor Antagonists/Interleukin-1β Inhibitors-Reference-Cited by-同舟云学术

Discovery of Potent and Selective Adamantane-Based Small-Molecule P2X7 Receptor Antagonists/Interleukin-1β Inhibitors

Published:2007-10-27 Issue:24 Volume:50 Page:5882-5885
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Furber Mark¹,Alcaraz Lilian¹,Bent Janice E.¹,Beyerbach Armin¹,Bowers Keith¹,Braddock Martin¹,Caffrey Moya V.¹,Cladingboel David¹,Collington John¹,Donald David K.¹,Fagura Malbinder¹,Ince Frank¹,Kinchin Elizabeth C.¹,Laurent Celine¹,Lawson Mandy¹,Luker Timothy J.¹,Mortimore Michael M. P.¹,Pimm Austen D.¹,Riley Robert J.¹,Roberts Nicola¹,Robertson Mark¹,Theaker Jill¹,Thorne Philip V.¹,Weaver Richard¹,Webborn Peter¹,Willis Paul¹

Affiliation:

1. Departments of Medicinal Chemistry, Discovery Bioscience, and Physical and Metabolic Science, AstraZeneca R&D Charnwood, Bakewell Road, Loughborough, Leics LE11 5RH, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm700949w

Reference25 articles.

1. Molecular Physiology of P2X Receptors

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