Synthesis and Applications of Polyamine Amino Acid Residues: Improving the Bioactivity of an Analgesic Neuropeptide, Neurotensin-Reference-Cited by-同舟云学术

Synthesis and Applications of Polyamine Amino Acid Residues: Improving the Bioactivity of an Analgesic Neuropeptide, Neurotensin

Published:2009-02-23 Issue:6 Volume:52 Page:1514-1517
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Zhang Liuyin¹,Lee Hee-Kyoung¹,Pruess Timothy H.¹,White H. Steve¹,Bulaj Grzegorz¹

Affiliation:

1. Department of Medicinal Chemistry and Department of Pharmacology and Toxicology, College of Pharmacy, University of Utah, Salt Lake City, Utah 84108

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm801481y

Reference35 articles.

1. Polyamine Modification Increases the Permeability of Proteins at the Blood-Nerve and Blood-Brain Barriers

2. Putrescine-Modified Nerve Growth Factor: Bioactivity, Plasma Pharmacokinetics, Blood-Brain/Nerve Barrier Permeability, and Nervous System Biodistribution

3. Design, Synthesis, and Characterization of High-Affinity, Systemically-Active Galanin Analogues with Potent Anticonvulsant Activities

4. Structural Requirements for a Lipoamino Acid in Modulating the Anticonvulsant Activities of Systemically Active Galanin Analogues

5. Cell-penetrating peptides: mechanism and kinetics of cargo delivery

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