The Intramolecular Asymmetric Pauson−Khand Cyclization as a Novel and General Stereoselective Route to Benzindene Prostacyclins: Synthesis of UT-15 (Treprostinil)-Reference-Cited by-同舟云学术

The Intramolecular Asymmetric Pauson−Khand Cyclization as a Novel and General Stereoselective Route to Benzindene Prostacyclins: Synthesis of UT-15 (Treprostinil)

Published:2004-02-19 Issue:6 Volume:69 Page:1890-1902
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Moriarty Robert M.¹,Rani Neena¹,Enache Livia A.¹,Rao Munagala S.¹,Batra Hitesh¹,Guo Liang¹,Penmasta Raju A.¹,Staszewski James P.¹,Tuladhar Sudersan M.¹,Prakash Om¹,Crich David¹,Hirtopeanu Anca¹,Gilardi Richard¹

Affiliation:

1. Department of Chemistry (M/C 111), University of Illinois at Chicago, Chicago, Illinois 60607, United Therapeutics, Chicago, Illinois 60612, deCODE Genetics, Inc., Chicago, Illinois 60612, Institute of Organic Chemistry, C.D. Nenitescu, Bucharest, Romania, and Laboratory for the Stucture of Matter, Naval Research Laboratory, Washington, DC 20375

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo0347720

Reference166 articles.

1. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation

2. The chemical structure of prostaglandin X (prostacyclin)

3. Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac arteries and inhibits platelet aggregation

Cited by 35 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Total Synthesis of Tetrahydrolipstatin, Its Derivatives, and Evaluation of Their Ability to Potentiate Multiple Antibiotic Classes against Mycobacterium Species;ACS Infectious Diseases;2021-09-03

2. Synthetic routes to treprostinil N-acyl methylsulfonamide;Tetrahedron Letters;2020-01

3. Biocatalysis as Useful Tool in Asymmetric Synthesis: An Assessment of Recently Granted Patents (2014–2019);Catalysts;2019-09-25

4. Total synthesis of natural (−)- and unnatural (+)-Melearoride A;Tetrahedron Letters;2019-03

5. Natural product syntheses via carbonylative cyclizations;Natural Product Reports;2019