Identification of Novel Inhibitors of M. tuberculosis Growth Using Whole Cell Based High-Throughput Screening-Reference-Cited by-同舟云学术

Identification of Novel Inhibitors of M. tuberculosis Growth Using Whole Cell Based High-Throughput Screening

Published:2012-05-21 Issue:8 Volume:7 Page:1377-1384
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Stanley Sarah A.¹²³,Grant Sarah Schmidt¹²³,Kawate Tomohiko¹²³,Iwase Noriaki¹,Shimizu Motohisa¹,Wivagg Carl¹³,Silvis Melanie¹,Kazyanskaya Edward¹,Aquadro John¹,Golas Aaron¹,Fitzgerald Michael¹,Dai Huanqin⁴,Zhang Lixin⁴,Hung Deborah T.¹²³

Affiliation:

1. The Broad Institute, 7 Cambridge Center, Cambridge, Massachusetts 02142, United States

2. Department of Molecular Biology and Center for Computational and Integrative Biology, Massachusetts General Hospital, 185 Cambridge St., Boston, Massachusetts 02114, United States

3. Department of Microbiology and Immunobiology, Harvard Medical School, 200 Longwood Ave, Boston, Massachusetts 02115, United States

4. Chinese Academy of Sciences, Institute of Microbiology, 8 Zhong Guan Cun Bei Er Tiao, Haidian District, Beijing, 100080, People’s Republic of China

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb300151m

Reference29 articles.

1. Global tuberculosis drug development pipeline: the need and the reality

2. A Diarylquinoline Drug Active on the ATP Synthase of Mycobacterium tuberculosis

3. Drugs versus bugs: in pursuit of the persistent predator Mycobacterium tuberculosis

4. A practical view of ‘druggability’

5. A chemical genetic screen in Mycobacterium tuberculosis identifies carbon-source-dependent growth inhibitors devoid of in vivo efficacy

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