1. School of Biomedical and Health Sciences, University of Western Sydney, Locked Bag 1797, Penrith South DC, 1797, NSW, Australia, Northern Institute of Cancer Research, Paul O’Gorman Building, Medical School, Framlington Place, University of Newcastle Upon Tyne, Newcastle Upon Tyne, NE2 4HH, United Kingdom, and Arthur Holmes Isotope Geology Laboratory, Department of Earth Sciences, University of Durham, Science Laboratories, South Road, Durham City, DH1 3LE, United Kingdom