Ranking High Affinity Ligands of Low Solubility by NMR Spectroscopy
Author:
Affiliation:
1. CNRS-UMR 8576, UGSF-IFR 147, Université des Sciences et Technologies de Lille, 59655 Villeneuve d'Ascq Cedex, France
2. ECNRS, UMR 7177, Laboratoire d'Infochimie, Université de Strasbourg, 67000 Strasbourg, France
Publisher
American Chemical Society (ACS)
Subject
Organic Chemistry,Drug Discovery,Biochemistry
Link
https://pubs.acs.org/doi/pdf/10.1021/ml200039u
Reference9 articles.
1. The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replicationin vitro
2. Debio 025, a Cyclophilin Binding Molecule, Is Highly Efficient in Clearing Hepatitis C Virus (HCV) Replicon-Containing Cells When Used Alone or in Combination with Specifically Targeted Antiviral Therapy for HCV (STAT-C) Inhibitors
3. Structural Basis for the Non-Immunosuppressive Character of the Cyclosporin A Analogue Debio 025
4. Conformational polymorphism of cyclosporin A
5. A fluorescence polarization-based assay for peptidyl prolyl cis/trans isomerase cyclophilin A
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