1. Institute of Biomaterials and Biomedical Engineering, ‡Terrence Donnelly Centre for Cellular and Biomolecular Research, Departments of §Chemistry, ∥Chemical Engineering, ⊥Materials Science and Engineering, #Department of Immunology, ¶Laboratory Medicine and Pathobiology, and △Sandra Rotman Centre for Global Health, University of Toronto, 160 College Street, Toronto, ON M5S 3E1, Canada