Specificity and Inhibitory Mechanism of Andrographolide and Its Analogues as Antiasthma Agents on NF-κB p50-Reference-Cited by-同舟云学术

Specificity and Inhibitory Mechanism of Andrographolide and Its Analogues as Antiasthma Agents on NF-κB p50

Published:2015-01-23 Issue:2 Volume:78 Page:208-217
ISSN:0163-3864
Container-title:Journal of Natural Products
language:en
Short-container-title:J. Nat. Prod.

Author:

Nguyen Van Sang¹,Loh Xin Yi²,Wijaya Hadhi³,Wang Jigang¹,Lin Qingsong¹,Lam Yulin³,Wong Wai-Shiu Fred²,Mok Yu Keung¹

Affiliation:

1. Department of Biological Sciences, National University of Singapore, 14 Science Drive 4, Singapore 117543

2. Department of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, Singapore and Immunology Program, Life Science Institute, National University of Singapore, Singapore 117456

3. Department of Chemistry, National University of Singapore, Singapore 117543

Funder

National University of Singapore

Biomedical Research Council - A STAR

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Complementary and alternative medicine,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Analytical Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/np5007179

Reference46 articles.

1. A Structural Guide to Proteins of the NF- B Signaling Module

2. The X-ray Crystal Structure of the NF-κB p50·p65 Heterodimer Bound to the Interferon β-κB Site

3. Crystal structure of p50/p65 heterodimer of transcription factor NF-κB bound to DNA

4. NF-κB p65 (RelA) homodimer uses distinct mechanisms to recognize DNA targets

5. Structure of the NF-κB p50 homodimer bound to DNA

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