Discovery of the CCR1 Antagonist, BMS-817399, for the Treatment of Rheumatoid Arthritis-Reference-Cited by-同舟云学术

Discovery of the CCR1 Antagonist, BMS-817399, for the Treatment of Rheumatoid Arthritis

Published:2014-09-03 Issue:18 Volume:57 Page:7550-7564
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Santella Joseph B.¹,Gardner Daniel S.¹,Duncia John V.¹,Wu Hong¹,Dhar Murali¹,Cavallaro Cullen¹,Tebben Andrew J.¹,Carter Percy H.¹,Barrish Joel C.¹,Yarde Melissa¹,Briceno Stephanie W.¹,Cvijic Mary Ellen¹,Grafstrom R. Robert¹,Liu Richard¹,Patel Sima R.¹,Watson Andrew J.¹,Yang Guchen¹,Rose Anne V.¹,Vickery Rodney D.¹,Caceres-Cortes Janet¹,Caporuscio Christian¹,Camac Daniel M.¹,Khan Javed A.¹,An Yongmi¹,Foster William R.¹,Davies Paul¹,Hynes John¹

Affiliation:

1. Bristol Myers Squibb Company, P.O. Box 4000, Princeton, New Jersey 08543-4000, United States

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm5003167

Reference44 articles.

1. Chemokine:Receptor Structure, Interactions, and Antagonism

2. MLN3897, a novel CCR1 inhibitor, impairs osteoclastogenesis and inhibits the interaction of multiple myeloma cells and osteoclasts

3. Chemokine Receptor CCR1 Regulates Inflammatory Cell Infiltration after Renal Ischemia-Reperfusion Injury

4. Overcoming hurdles in developing successful drugs targeting chemokine receptors

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