A Direct Catalytic Asymmetric Mannich-type Reaction via a Dinuclear Zinc Catalyst:  Synthesis of Either anti- or syn-α-Hydroxy-β-Amino Ketones

Author:

Trost Barry M.1,Jaratjaroonphong Jaray1,Reutrakul Vichai1

Affiliation:

1. Department of Chemistry, Stanford University, Stanford, California 94305-5080, and Department of Chemistry, Faculty of Science, Mahidol University, Rama VI Road, Bangkok 10400, Thailand

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Reference8 articles.

1. Reviews:  (a) Denmark, S. E.; Nicaise, O. J.C. InComprehensive AsymmetricCatalysis; Jacobsen, E. N., Pfaltz, A., Yamamoto, H., Eds.; Springer:  Heidelberg, 1999; pp 923−961. (b) Kleinmann, E. F. InComprehensiveOrganic Synthesis; Trost, B. M., Ed.; Pergamon Press:  New York. 1991; Vol. 2, Chapter 4.1. (c) Arend, M.; Westermann, B.; Risch, N.Angew.Chem., Int. Ed.1998,37, 1044. (d) Kobayashi, S.; Ishitani, H.Chem. Rev.1999,99, 1069.

2. The Direct Catalytic Asymmetric Mannich Reaction

3. Catalytic Asymmetric Direct Mannich Reactions of Carbonyl Compounds withα-Imino Esters

4. Asymmetric Catalysis Special Feature Part I: Catalytic asymmetric addition of diorganozinc reagents to N-phosphinoylalkylimines

5. Configurational stability of chiral, nonconjugated nitrogen-substituted organolithium compounds generated by tin-lithium exchange of N-[(1-tri-n-butylstannyl)alkyl]imidazolidin-2-ones and -oxazolidin-2-ones

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