Evaluation of Selected Chemotypes in Coupled Cellular and Molecular Target-Based Screens Identifies Novel HIV-1 Zinc Finger Inhibitors-Reference-Cited by-同舟云学术

Evaluation of Selected Chemotypes in Coupled Cellular and Molecular Target-Based Screens Identifies Novel HIV-1 Zinc Finger Inhibitors

Published:1996-01-01 Issue:19 Volume:39 Page:3606-3616
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Rice William G.¹,Turpin Jim A.¹,Schaeffer Catherine A.¹,Graham Lisa¹,Clanton David¹,Buckheit, Robert W.¹,Zaharevitz Daniel¹,Summers Michael F.¹,Wallqvist Anders¹,Covell David G.¹

Affiliation:

1. Laboratory of Antiviral Drug Mechanisms and Anti-AIDS Virus Drug Screening Laboratory, Developmental Therapeutics Program, Division of Cancer Treatment, Diagnosis and Centers, National Cancer Institute−Frederick Cancer Research and Development Center, SAIC Frederick, Frederick, Maryland 21702, Virology Research Group, Southern Research Institute−Frederick Research Center, 431 Aviation Way, Frederick, Maryland 21702, Developmental Therapeutics Program, Division of Cancer Treatment, Diagnosis and Centers,...

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm960375o

Reference29 articles.

1. Primary structure of the low molecular weight nucleic acid-binding proteins of murine leukemia viruses.

2. The nucleocapsid protein isolated from HIV-1 particles binds zinc and forms retroviral-type zinc fingers

3. Nucleocapsid zinc fingers detected in retroviruses: EXAFS studies of intact viruses and the solution-state structure of the nucleocapsid protein from HIV-1

4. Amino acid sequence homology in gag region of reverse transcribing elements and the coat protein gene of cauliflower mosaic virus

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