1. Laboratory for Medicinal Chemistry (FFW), Ghent University, Harelbekestraat 72, 9000 Ghent, Belgium, Laboratory for Molecular Immunology and Inflammation, Department of Rheumatology, Ghent University Hospital, Ghent University, De Pintelaan 185, 9000 Ghent, Belgium, Division of Cell Biology, La Jolla Institute for Allergy and Immunology, La Jolla, California, and School of Chemistry, University of Southampton, Highfield, Southampton SO17 1BJ, U.K.