1. Research and Development Center, Sunstar Inc., 3-1 Asahi-machi, Takatsuki, Osaka 569-1195, Japan; Department of Molecular Medicine, Osaka University Medical School, 2-2 Yamadaoka, Suita, Osaka 565-0871, Japan; Department of Nutritional Science, Faculty of Health and Welfare Science, Okayama Prefectural University, 111 Soja, Okayama 719-1197, Japan; and Department of Internal Medicine III, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, Hyogo 663-8131, Japan