Synthetic mRNA Splicing Modulator Compounds with in Vivo Antitumor Activity
Author:
Affiliation:
1. Department of Chemical Biology and Therapeutics
2. Department of Pathology
3. Department of Genetics and Tumor Cell Biology
4. Department of Oncology,
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm901215m
Reference40 articles.
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3. Spliceostatin A targets SF3b and inhibits both splicing and nuclear retention of pre-mRNA
4. Splicing factor SF3b as a target of the antitumor natural product pladienolide
5. Pladienolides, New Substances from Culture of Streptomyces platensis Mer-11107 III. In Vitro and In Vivo Antitumor Activities
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