pH-Dependent Solubility and Permeability Criteria for Provisional Biopharmaceutics Classification (BCS and BDDCS) in Early Drug Discovery-Reference-Cited by-同舟云学术

pH-Dependent Solubility and Permeability Criteria for Provisional Biopharmaceutics Classification (BCS and BDDCS) in Early Drug Discovery

Published:2012-04-26 Issue:5 Volume:9 Page:1199-1212
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Varma Manthena V.¹,Gardner Iain²,Steyn Stefanus J.¹,Nkansah Paul¹,Rotter Charles J.¹,Whitney-Pickett Carrie¹,Zhang Hui¹,Di Li¹,Cram Michael²,Fenner Katherine S.²,El-Kattan Ayman F.¹

Affiliation:

1. Pfizer Global Research and Development, Pfizer Inc., Groton, Connecticut 06340, United States

2. Pfizer Global Research and Development, Pfizer Inc., Sandwich, Kent, CT13 9NJ, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp2004912

Reference45 articles.

1. CDER/FDA. Guidance for industry: Waiver of in vivo bioavailability and bioequivalence studies for imidiate-release solid oral dosage forms based on a biopharmaceutics classification system. Center for Drug Evaluation and Research, 2000.

2. Human Intestinal Permeability

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