Arylaminoethyl Amides as Novel Non-Covalent Cathepsin K Inhibitors
Author:
Affiliation:
1. Arthrithis & Bone Metabolism Therapeutic Area and Central Technologies, Novartis Pharma Research, CH-4002 Basel, Switzerland
Publisher
American Chemical Society (ACS)
Subject
Drug Discovery,Molecular Medicine
Link
https://pubs.acs.org/doi/pdf/10.1021/jm010801s
Reference11 articles.
1. Molecular Cloning of Human cDNA for Cathepsin K: Novel Cysteine Proteinase Predominantly Expressed in Bone
2. Cathepsin K, but Not Cathepsins B, L, or S, Is Abundantly Expressed in Human Osteoclasts
3. The Collagenolytic Activity of Cathepsin K Is Unique among Mammalian Proteinases
4. Proteolytic Activity of Human Osteoclast Cathepsin K
5. Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice
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