1. Department of Complex Prescription of Chinese Materia Medica, China Pharmaceutical University, Nanjing 210009, Jiangsu, People's Republic of China, Institute for Health Research and Policy, London Metropolitan University, 166-220 Holloway Road, London, UK, N7 8DB, and Institute of Chinese Materia Medica, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, People's Republic of China