Discovery of Pyrrolopyridine−Pyridone Based Inhibitors of Met Kinase: Synthesis, X-ray Crystallographic Analysis, and Biological Activities-Reference-Cited by-同舟云学术

Discovery of Pyrrolopyridine−Pyridone Based Inhibitors of Met Kinase: Synthesis, X-ray Crystallographic Analysis, and Biological Activities

Published:2008-08-09 Issue:17 Volume:51 Page:5330-5341
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Kim Kyoung Soon¹,Zhang Liping¹,Schmidt Robert¹,Cai Zhen-Wei¹,Wei Donna¹,Williams David K.¹,Lombardo Louis J.¹,Trainor George L.¹,Xie Dianlin¹,Zhang Yaquan¹,An Yongmi¹,Sack John S.¹,Tokarski John S.¹,Darienzo Celia¹,Kamath Amrita¹,Marathe Punit¹,Zhang Yueping¹,Lippy Jonathan¹,Jeyaseelan Robert¹,Wautlet Barri¹,Henley Benjamin¹,Gullo-Brown Johnni¹,Manne Veeraswamy¹,Hunt John T.¹,Fargnoli Joseph¹,Borzilleri Robert M.¹

Affiliation:

1. Departments of Oncology Chemistry, Oncology Drug Discovery, Structural Biology and Modeling, and Metabolism and Pharmacokinetics, Bristol-Myers Squibb Pharmaceutical Research & Development, P.O. Box 4000, Princeton, New Jersey 08543-4000

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm800476q

Reference26 articles.

1. Scatter-factor and semaphorin receptors: cell signalling for invasive growth

2. Targeting the c-Met Signaling Pathway in Cancer: Fig. 1.

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