Synthesis and Antiviral Activity of the Carbocyclic Analogue of the Highly Potent and Selective Anti-VZV Bicyclo Furano Pyrimidines-Reference-Cited by-同舟云学术

Synthesis and Antiviral Activity of the Carbocyclic Analogue of the Highly Potent and Selective Anti-VZV Bicyclo Furano Pyrimidines

Published:2007-12-01 Issue:26 Volume:50 Page:6485-6492
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Migliore Marco D.¹,Zonta Nicola¹,McGuigan Christopher¹,Henson Geoffrey¹,Andrei Graciela¹,Snoeck Robert¹,Balzarini Jan¹

Affiliation:

1. Welsh School of Pharmacy, Cardiff University, Redwood Building, King Edward Vll Avenue, Cardiff, United Kingdom, Inhibitex, 9005 Westside Parkway, Alpharetta, Georgia 30004, and Rega Institute for Medical Research, Katholieke Universiteit Leuven, B- 3000 Leuven, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm070357e

Reference17 articles.

1. Highly Potent and Selective Inhibition of Varicella-Zoster Virus by Bicyclic Furopyrimidine Nucleosides Bearing an Aryl Side Chain

2. Chemotherapy of varicella-zoster virus by a novel class of highly specific anti-VZV bicyclic pyrimidine nucleosides

3. Lack of Susceptibility of Bicyclic Nucleoside Analogs, Highly Potent Inhibitors of Varicella-Zoster Virus, to the Catabolic Action of Thymidine Phosphorylase and Dihydropyrimidine Dehydrogenase

4. Henson, Dr. G.Inhibitex, personal communication.

5. Cerium(IV)-mediated halogenation at C-5 of uracil derivatives

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