Regioisomerism in the Synthesis of a Chiral Aminotetralin Drug Compound: Unraveling Mechanistic Details and Diastereomer-Specific In-Depth NMR Investigations-Reference-Cited by-同舟云学术

Regioisomerism in the Synthesis of a Chiral Aminotetralin Drug Compound: Unraveling Mechanistic Details and Diastereomer-Specific In-Depth NMR Investigations

Published:2012-06-13 Issue:13 Volume:77 Page:5503-5514
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Schuisky Peter¹,Federsel Hans-Jürgen¹,Tian Wei¹

Affiliation:

1. Pharmaceutical Development, AstraZeneca, 151 85 Södertälje, Sweden

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/jo300277y

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4. Berg, S.; Linderberg, M.; Ross, S. B.; Thorberg, S.O.; Ulff, B.PCT Int. Appl. WO 9,905,134, 1999.

5. Construction of a Chiral Central Nervous System (CNS)-Active Aminotetralin Drug Compound Based on a Synthesis Strategy Using Multitasking Properties of (S)-1-Phenylethylamine

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