Alkylidene Oxapenem β-Lactamase Inhibitors Revisited: Potent Broad Spectrum Activity but New Stability Challenges-Reference-Cited by-同舟云学术

Alkylidene Oxapenem β-Lactamase Inhibitors Revisited: Potent Broad Spectrum Activity but New Stability Challenges

Published:2014-06-25 Issue:8 Volume:5 Page:915-920
ISSN:1948-5875
Container-title:ACS Medicinal Chemistry Letters
language:en
Short-container-title:ACS Med. Chem. Lett.

Author:

Miller Matthew D.¹,Kale Manoj²,Reddy Kishore²,Tentarelli Sharon¹,Zambrowski Mark¹,Zhang Minli¹,Palmer Tiffany¹,Breen John¹,Lahiri Sushmita¹,Shirude Pravin S.²,Verheijen Jeroen C.¹

Affiliation:

1. Infection iMed, AstraZeneca, 35 Gatehouse Drive, Waltham, Massachusetts 02451, United States

2. Department of Medicinal Chemistry, AstraZeneca India Pvt. Ltd, Avishkar, Bellary Road, Bangalore 560024, India

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/ml5001855

Reference15 articles.

1. The future of the β-lactams

2. New β-lactam antibiotics and β-lactamase inhibitors

3. Understanding the longevity of the β-lactam antibiotics and of antibiotic/β-lactamase inhibitor combinations

4. Bacterial Resistance to β-Lactam Antibiotics: Compelling Opportunism, Compelling Opportunity

5. Three Decades of β-Lactamase Inhibitors

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