Discovery of Functionally Selective 7,8,9,10-Tetrahydro-7,10-ethano-1,2,4-triazolo[3,4-a]phthalazines as GABAA Receptor Agonists at the α3 Subunit-Reference-Cited by-同舟云学术

Discovery of Functionally Selective 7,8,9,10-Tetrahydro-7,10-ethano-1,2,4-triazolo[3,4-a]phthalazines as GABAA Receptor Agonists at the α3 Subunit

Published:2005-02-04 Issue:5 Volume:48 Page:1367-1383
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Russell Michael G. N.¹,Carling Robert W.¹,Atack John R.¹,Bromidge Frances A.¹,Cook Susan M.¹,Hunt Peter¹,Isted Catherine¹,Lucas Matt¹,McKernan Ruth M.¹,Mitchinson Andrew¹,Moore Kevin W.¹,Narquizian Robert¹,Macaulay Alison J.¹,Thomas David¹,Thompson Sally-Anne¹,Wafford Keith A.¹,Castro José L.¹

Affiliation:

1. Merck Sharp & Dohme Research Laboratories, Neuroscience Research Centre, Terlings Park, Eastwick Road, Harlow, Essex CM20 2QR, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm040883v

Reference50 articles.

1. An update on GABAA receptors

2. Which GABAA-receptor subtypes really occur in the brain?

3. Mapping of the Benzodiazepine Recognition Site on GABA-A Receptors

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