Syntheses, Radiolabelings, and in Vitro Evaluations of Fluorinated PET Radioligands of 5-HT6 Serotoninergic Receptors-Reference-Cited by-同舟云学术

Syntheses, Radiolabelings, and in Vitro Evaluations of Fluorinated PET Radioligands of 5-HT6 Serotoninergic Receptors

Published:2014-04-29 Issue:9 Volume:57 Page:3884-3890
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Colomb Julie¹²,Becker Guillaume³²⁴,Fieux Sylvain³²,Zimmer Luc³²⁴,Billard Thierry¹²

Affiliation:

1. Institute of Chemistry and Biochemistry (ICBMS-UMR CNRS 5246), University of Lyon, University Lyon 1, CNRS, 43 Boulevard du 11 Novembre 1918, 69622 Lyon, France

2. CERMEP-In Vivo Imaging, Groupement Hospitalier Est, 59 Boulevard Pinel, 69003 Lyon, France

3. Lyon Neuroscience Research Center (UMR 5292, U 1028), University of Lyon, University Lyon 1, CNRS, INSERM, 59 Boulevard Pinel, 69003 Lyon, France

4. Hospices Civils de Lyon, Neurological Hospital, 59 Boulevard Pinel, 69003 Lyon, France

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm500372e

Reference48 articles.

1. A Novel Rat Serotonin (5-HT6) Receptor: Molecular Cloning, Localization and Stimulation of cAMP Accumulation

2. Cloning, Characterization, and Chromosomal Localization of a Human 5-HT6 Serotonin Receptor

3. The 5-Hydroxytryptamine6Receptor-Selective radioligand [3H]Ro 63–0563 Labels 5-Hydroxytryptamine Receptor Binding Sites in Rat and Porcine Striatum

4. The distribution of 5-HT6 receptors in rat brain: an autoradiographic binding study using the radiolabelled 5-HT6 receptor antagonist [125I]SB-258585

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