Modeling of Human Cytochrome P450-Mediated Drug Metabolism Using Unsupervised Machine Learning Approach-Reference-Cited by-同舟云学术

Modeling of Human Cytochrome P450-Mediated Drug Metabolism Using Unsupervised Machine Learning Approach

Published:2003-07-23 Issue:17 Volume:46 Page:3631-3643
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Korolev Dmitry¹,Balakin Konstantin V.¹,Nikolsky Yuri¹,Kirillov Eugene¹,Ivanenkov Yan A.¹,Savchuk Nikolay P.¹,Ivashchenko Andrey A.¹,Nikolskaya Tatiana¹

Affiliation:

1. GeneGo, Inc., 227 South Berrien Street, New Buffalo, Michigan 49117, and Chemical Diversity Labs, Inc., 11558 Sorrento Valley Road, San Diego, California 92121

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm030102a

Reference47 articles.

1. (a) Darvas, F. MetabolExpert: an Expert System for Predicting the Metabolism of Substances. InQSAR in Environmental Toxicology II; Kaiser, K. L., Ed.; Reidel Co. Dordrecht, 1987; pp 71−81.

2. (b) Darvas, F.; Marokházi, S.; Kormos, P.; Kulkarni, G.; Kalász, H.; Papp, Á. MetabolExpert: Its Use in Metabolism Research and in Combinatorial Chemistry. InDrug Metabolism.Databases and High-Throughput TestingDuring Drug Design and Development; Erhardt, P. W., Ed.; Blackwell Science Ltd., 1999; pp 237−270.

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