Aptamers Selected for Higher-Affinity Binding Are Not More Specific for the Target Ligand-Reference-Cited by-同舟云学术

Aptamers Selected for Higher-Affinity Binding Are Not More Specific for the Target Ligand

Published:2006-05-27 Issue:24 Volume:128 Page:7929-7937
ISSN:0002-7863
Container-title:Journal of the American Chemical Society
language:en
Short-container-title:J. Am. Chem. Soc.

Author:

Carothers James M.¹,Oestreich Stephanie C.¹,Szostak Jack W.¹

Affiliation:

1. Contribution from the Department of Molecular Biology, and Center for Computational and Integrative Biology 7215, Simches Research Center, Massachusetts General Hospital, 185 Cambridge Street, Boston, Massachusetts 02114

Publisher

American Chemical Society (ACS)

Subject

Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis

Link

https://pubs.acs.org/doi/pdf/10.1021/ja060952q

Reference37 articles.

1. In vitro selection of RNA molecules that bind specific ligands

2. Carothers, J. M.; Szostak, J. W. InThe Aptamer Handbook: FunctionalOligonucleotides and their Applications; Klussmann, S., Ed.; Wiley-VCH: Berlin, 2006; pp 3−28.

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