Crystal Structures of Rat Thymidylate Synthase Inhibited by Tomudex, a Potent Anticancer Drug,-Reference-Cited by-同舟云学术

Crystal Structures of Rat Thymidylate Synthase Inhibited by Tomudex, a Potent Anticancer Drug,

Published:1998-12-29 Issue:3 Volume:38 Page:1087-1094
ISSN:0006-2960
Container-title:Biochemistry
language:en
Short-container-title:Biochemistry

Author:

Sotelo-Mundo Rogerio R.¹,Ciesla Joanna¹,Dzik Jolanta M.¹,Rode Wojciech¹,Maley Frank¹,Maley Gladys F.¹,Hardy Larry W.¹,Montfort William R.¹

Affiliation:

1. Department of Biochemistry, University of Arizona, Tucson, Arizona 85721, Nencki Institute of Experimental Biology, Polish Academy of Sciences, 3 Pasteur Street, 02-093 Warszawa, Poland, Wadsworth Center, New York State Department of Health, Albany, New York, 12201, and Department of Pharmacology and Molecular Genetics, University of Massachusetts Medical Center, 55 Lake Avenue North, Worcester, Massachusetts, 01655

Publisher

American Chemical Society (ACS)

Subject

Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/bi981881d

Reference49 articles.

1. Thymidylate synthase: Structure, inhibition, and strained conformations during catalysis

2. Stereochemistry of a multistep/bipartite methyl transfer reaction: thymidylate synthase

3. THE CATALYTIC MECHANISM AND STRUCTURE OF THYMIDYLATE SYNTHASE

4. Structural aspects of the inhibition and catalytic mechanism of thymidylate synthase.

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