Discovery of Novel Small Molecule Orally Bioavailable C−X−C Chemokine Receptor 4 Antagonists That Are Potent Inhibitors of T-Tropic (X4) HIV-1 Replication-Reference-Cited by-同舟云学术

Discovery of Novel Small Molecule Orally Bioavailable C−X−C Chemokine Receptor 4 Antagonists That Are Potent Inhibitors of T-Tropic (X4) HIV-1 Replication

Published:2010-03-19 Issue:8 Volume:53 Page:3376-3388
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Skerlj Renato T.¹,Bridger Gary J.²,Kaller Al²,McEachern Ernest J.²,Crawford Jason B.²,Zhou Yuanxi²,Atsma Bem²,Langille Jonathon²,Nan Susan²,Veale Duane²,Wilson Trevor²,Harwig Curtis²,Hatse Sigrid³,Princen Katrien³,De Clercq Erik³,Schols Dominique³

Affiliation:

1. Genzyme Corp., 153 Second Avenue, Waltham, Massachusetts 02451

2. AnorMED, Inc., 200-20353 64th Avenue, Langley, British Columbia, V2Y 1N5, Canada

3. Rega Institute for Medical Research, Katholieke Universiteit Leuven, Minderbroedersstraat 10, B-3000 Leuven, Belgium

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm100073m

Reference45 articles.

1. Antiretroviral Treatment for Adult HIV Infection in 2002