HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells-Reference-Cited by-同舟云学术

HDAC6 Inhibitors Modulate Lys49 Acetylation and Membrane Localization of β-Catenin in Human iPSC-Derived Neuronal Cells

Published:2015-01-08 Issue:3 Volume:10 Page:883-890
ISSN:1554-8929
Container-title:ACS Chemical Biology
language:en
Short-container-title:ACS Chem. Biol.

Author:

Iaconelli Jonathan¹²,Huang Joanne H.¹²,Berkovitch Shaunna S.¹²,Chattopadhyay Shrikanta²³,Mazitschek Ralph²⁴,Schreiber Stuart L.²⁵,Haggarty Stephen J.¹,Karmacharya Rakesh¹²⁶

Affiliation:

1. Center for Experimental Drugs and Diagnostics, Psychiatric and Neurodevelopmental Genetics Unit, Center for Human Genetic Research, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts 02114, United States

2. Center for the Science of Therapeutics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, United States

3. MGH Cancer Center, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts 02114, United States

4. Center for Systems Biology, Harvard Medical School and Massachusetts General Hospital, Boston, Massachusetts 02114, United States

5. Howard Hughes Medical Institute, Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138, United States

6. Schizophrenia and Bipolar Disorder Program, McLean Hospital, Belmont, Massachusetts 02478, United States

Funder

National Cancer Institute

National Institute on Drug Abuse

National Institute of Mental Health

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

Molecular Medicine,General Medicine,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/cb500838r

Reference57 articles.

1. Wnt/β-Catenin Signaling and Disease

2. The many faces and functions of β-catenin

3. The dynamic role of beta-catenin in synaptic plasticity

4. The Wnt cries many: Wnt regulation of neurogenesis through tissue patterning, proliferation, and asymmetric cell division

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