Identification of a Promising Drug Candidate for the Treatment of Type 2 Diabetes Based on a P2Y1 Receptor Agonist-Reference-Cited by-同舟云学术

Identification of a Promising Drug Candidate for the Treatment of Type 2 Diabetes Based on a P2Y1 Receptor Agonist

Published:2012-08-20 Issue:17 Volume:55 Page:7623-7635
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Yelovitch Shir¹,Barr Haim M.²,Camden Jean³,Weisman Gary A.³,Shai Ela⁴,Varon David⁴,Fischer Bilha¹

Affiliation:

1. Department of Chemistry, Bar-Ilan University, Ramat-Gan 52900, Israel

2. BioLineRx Ltd., 23 Hillel Street, Jerusalem 91450, Israel

3. Biochemistry Department, 540E Bond Life Sciences Center, University of Missouri, Columbia, Missouri 65211, United States

4. Department of Hematology, Hadassah University Hospital, Jerusalem 91120, Israel

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm3006355

Reference53 articles.

1. Stefek, M., Ed.Advances in Molecular Mechanisms and Pharmacology of Diabetic Complications;Transworld Research Network:Kerala, India, 2010; p341ff.

2. Insulin resistance and fuel homeostasis: the role of AMP-activated protein kinase

3. Combination of Oral Antidiabetic Drugs and Insulin in the Treatment of Non-Insulin-Dependent Diabetes

4. Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33)

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