Diastereomeric Spirooxindoles as Highly Potent and Efficacious MDM2 Inhibitors
Author:
Affiliation:
1. Sanofi Research & Development, Montpellier, France
2. Sanofi Research & Development, Vitry-sur-Seine, France
3. Naval Research Laboratory, Code 6930, 4555 Overlook Avenue, Washington, D.C. 20375, United States
Publisher
American Chemical Society (ACS)
Subject
Colloid and Surface Chemistry,Biochemistry,General Chemistry,Catalysis
Link
https://pubs.acs.org/doi/pdf/10.1021/ja3125417
Reference27 articles.
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3. Construction of Spiro[pyrrolidine‐3,3′‐oxindoles] − Recent Applications to the Synthesis of Oxindole Alkaloids
4. dBartkovitz, D. J.; Chu, X.J.; Ding, Q.; Graves, B. J.; Jiang, N.; Zhang, J.; Zhang, Z.PCT patent application WO 2011/067185, 2011
5. Organocatalytic Synthesis of Spiro[pyrrolidin-3,3′-oxindoles] with High Enantiopurity and Structural Diversity
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