Acid-Induced Activated Cell-Penetrating Peptide-Modified Cholesterol-Conjugated Polyoxyethylene Sorbitol Oleate Mixed Micelles for pH-Triggered Drug Release and Efficient Brain Tumor Targeting Based on a Charge Reversal Mechanism

Author:

Tian Yu1,Mi Gujie2,Chen Qian1,Chaurasiya Birendra1,Li Yanan1,Shi Di2,Zhang Yong3,Webster Thomas J.2ORCID,Sun Chunmeng1ORCID,Shen Yan1

Affiliation:

1. State Key Laboratory of Natural Medicines, Department of Pharmaceutics, School of Pharmacy, China Pharmaceutical University, Nanjing 210009, China

2. Department of Chemical Engineering, 313 Snell Engineering Center, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States

3. Children’s Hospital of Nanjing Medical University, Nanjing 210008, China

Funder

Ministry of Science and Technology of the People's Republic of China

Natural Science Foundation of Jiangsu Province

Nanjing Medical University

National Natural Science Foundation of China

Priority Academic Program Development of Jiangsu Higher Education Institutions

Publisher

American Chemical Society (ACS)

Subject

General Materials Science

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