Tandem Cyclopropanation with Dibromomethane under Grignard Conditions

Author:

Brunner Gerhard1,Eberhard Laura1,Oetiker Jürg1,Schröder Fridtjof1

Affiliation:

1. Research Chemistry Department, Givaudan Schweiz AG, CH-8600 Dübendorf, Switzerland

Publisher

American Chemical Society (ACS)

Subject

Organic Chemistry

Reference84 articles.

1. Parts of this investigation were presented at the “Scale-Up of Chemical Processes” Scientific Update Conference,Boston, MA, August 29−31, 2007.

2. Development of Transition Metal-Mediated Cyclopropanation Reactions

3. The reactivity order of dihalomethanes is in accordance with that of the radical halogen abstraction from these compounds. See for example:

4. Mechanism of Reduction of Alkyl Halides by Organotin Hydrides

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