Uptake of Compounds That Selectively Kill Multidrug-Resistant Cells: The Copper Transporter SLC31A1 (CTR1) Increases Cellular Accumulation of the Thiosemicarbazone NSC73306-Reference-Cited by-同舟云学术

Uptake of Compounds That Selectively Kill Multidrug-Resistant Cells: The Copper Transporter SLC31A1 (CTR1) Increases Cellular Accumulation of the Thiosemicarbazone NSC73306

Published:2014-06-17 Issue:8 Volume:11 Page:2692-2702
ISSN:1543-8384
Container-title:Molecular Pharmaceutics
language:en
Short-container-title:Mol. Pharmaceutics

Author:

Fung King Leung¹,Tepede Abisola K.¹,Pluchino Kristen M.¹,Pouliot Lynn M.¹,Pixley Jessica N.¹,Hall Matthew D.¹,Gottesman Michael M.¹

Affiliation:

1. Laboratory of Cell Biology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, United States

Funder

National Institutes of Health

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Pharmaceutical Science,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/mp500114e

Reference54 articles.

1. Human Multidrug-Resistant Cell Lines: Increased mdr 1 Expression Can Precede Gene Amplification

2. Expression of a multidrug-resistance gene in human tumors and tissues.

3. Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding