Systems Toxicology: Integrated Genomic, Proteomic and Metabonomic Analysis of Methapyrilene Induced Hepatotoxicity in the Rat-Reference-Cited by-同舟云学术

Systems Toxicology: Integrated Genomic, Proteomic and Metabonomic Analysis of Methapyrilene Induced Hepatotoxicity in the Rat

Published:2006-06-15 Issue:7 Volume:5 Page:1586-1601
ISSN:1535-3893
Container-title:Journal of Proteome Research
language:en
Short-container-title:J. Proteome Res.

Author:

Craig Andrew¹,Sidaway James¹,Holmes Elaine¹,Orton Terry¹,Jackson David¹,Rowlinson Rachel¹,Nickson Janice¹,Tonge Robert¹,Wilson Ian¹,Nicholson Jeremy¹

Affiliation:

1. Biological Chemistry, Biomedical Sciences Division, Faculty of Life Sciences, Imperial College London, Sir Alexander Fleming Building, South Kensington, London SW7 2AZ, United Kingdom, Safety Assessment, AstraZeneca, Alderley Park, Macclesfield, Cheshire SK104 TG, United Kingdom, Pathways, Discovery Enabling Capabilities and Sciences, AstraZeneca, Alderley Park, Macclesfield, Cheshire SK10 4TG, United Kingdom, and Department of Drug Metabolism and Pharmacokinetics, AstraZeneca, Alderley Park,...

Publisher

American Chemical Society (ACS)

Subject

General Chemistry,Biochemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/pr0503376

Reference45 articles.

1. Metabolic trajectory characterisation of xenobiotic-induced hepatotoxic lesions using statistical batch processing of NMR data

2. Metabolic Profiling of Chronic Cadmium Exposure in the Rat

3. Combination of ‘omics’ data to investigate the mechanism(s) of hydrazine-induced hepatotoxicity in Rats and to identify potential biomarkers

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